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Symbol Name ID |
Lama5
laminin, alpha 5 MGI:105382 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | renal/urinary system phenotype |
abnormal glomerular capillary endothelium morphology |
abnormal glomerular capillary morphology |
abnormal mesangial cell morphology |
increased kidney apoptosis |
kidney cyst |
polycystic kidney |
enlarged kidney |
increased urine protein level |
hematuria |
tubulointerstitial nephritis |
abnormal kidney morphology |
abnormal podocyte morphology |
podocyte foot process effacement |
abnormal renal glomerulus basement membrane morphology |
increased renal glomerulus basement membrane thickness |
expanded mesangial matrix |
glomerulosclerosis |
abnormal kidney development |
renal interstitial fibrosis |
small kidney |
dilated renal tubule |
absent kidney |
absent ureter |
impaired branching involved in ureteric bud morphogenesis |
kidney failure |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||
| Lama5b2b2966.1Clo/Lama5b2b2966.1Clo | |||||||||||||||||||||||||||
| Lama5tm1Jhm/Lama5tm1Jhm | |||||||||||||||||||||||||||
| Lama5tm3Jhm/Lama5tm3Jhm | |||||||||||||||||||||||||||
| Lama5tm3Jhm/Lama5tm3Jhm Tg(Nphs1-flpo)1Jhm/0 (conditional) |
* | ||||||||||||||||||||||||||
| Lama5tm2Jhm/Lama5tm1Jhm Tg(NPHS2-cre)295Lbh/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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